On February 26th, a research team from Nagoya University in Japan published an innovative study titled “Internal Hat Initiation Translation” (ICIT) mechanism in the latest issue of the journal Nature Biotechnology. Under this mechanism, mRNA that appears to be wearing a hat can produce over 200 times more protein, providing a new approach for treating cancer and diseases with abnormal protein synthesis. This achievement has brought revolutionary progress to mRNA medicine and revealed the possibility of regulating the translation process through the interaction between long non coding RNA and mRNA, indicating that more new therapeutic methods based on this mechanism may be developed in the future.
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